From what I've read, especially regarding later last season, Oregon's offensive line play was not optimal for multiple reasons. There were a lot of injuries, Mario Cristobal checked out the last few games with his eyes on moving to Miami, and Mario`s plain vanilla offensive schemes put undue pressure on the offensive line.
Regarding the latter point, Mario would try to pound the ball up the middle so often, just hoping that the sheer physicality of his line would open gaps, that defenses quickly learned to stack the box and stifle those plays. It doesn't look like Lanning and crew will suffer from Mario short-sidedness, and Oregon's offensive line appears to be pretty healthy and deep at this point. I've read a few of Charles Fischer's articles on this site that question the ability of Oregon's offensive tackles to effectively block pass rushes.
I don't have Charles'experience and expertise regarding such issues, but I've learned from experience that it's typically a good idea to trust his analyses.