Looks like the end for the intersectional matchup, and why not?

ND makes money off the series. ND's recruiting benefits from the series.

USC gets a jeweled stick if it wins. 🤪 A B1G SC does not need another trip east every other season.

SC offered to compromise and continue the series if the game was played earlier in the year at a neutral site. Allegiant Stadium in Las Vegas is what SC offered as a neutral venue.

https://sports.yahoo.com/college-football/breaking-news/article/sources-notre-dame-usc-rivalry-series-ending-next-year-as-irish-finalize-2-year-deal-with-byu-165245493.html

SC wants to play the game in September, not middle/late in the Big Ten portion of the schedule.

Notre Dame wants to play it late in the season because most years USC will be ranked, and Notre Dame wants a ranked game on the resume late in the season as the CFP seeds are being announced. This year, after Sep. 13, they had two ranked games: USC and Pitt. With a partial ACC schedule, they are nervous about not having a ranked opponent late. They saw what happened to Miami when the last half of the Hurricanes schedule became weak.

They both simply have different scheduling needs. Neither wants to compromise.

I don’t care much about Notre Dame or USC, but I do hate to see traditional rivalry games come to an end.